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    Drug interactions. Some products that may interact with this drug include: mifepristone. Other medications can affect the removal of dabigatran from your body, which may affect how dabigatran works. Examples include cobicistat, cyclosporine, dronedarone, ketoconazole, rifampin. Missed dose. If you miss a dose of Pradaxa, take it as soon as you remember. If your next dose is less than 6 hours away, skip the missed dose. Do not take two doses of Pradaxa at the same time. Do not take extra medicine to make up the missed dose. Try not to miss any doses of Pradaxa to best prevent a stroke.
    Directions. Take this medication by mouth with or without food as directed by your doctor, usually twice a day. To prevent clots after hip or knee replacement surgery, take it as directed by your doctor, usually once a day. Avoid antacids within 24 hours after surgery, or dabigatran may not work as well. Swallow the capsules whole with a full glass of water (8 ounces/240 milliliters). Do not crush, chew, or break open the capsules. Doing so can release all of the drug at once, increasing the risk of side effects. Do not put this medication in a pill box or medication reminder box. It must be kept tightly closed in the original bottle (or blister package) to protect it from moisture. It is very important to take it exactly as directed. Do not increase your dose or take this drug more often than directed. Do not stop taking this medication without consulting your doctor.
    Receive Eliquis and other prescription medications for the set price of $35.00 per month per medication. Eliquis (apixaban) is prescribed to Americans who suffer from a number of heart situations, including nonvalvular atrial fibrillation. Dabigatran (Pradaxa) is an expensive drug used to lower the chance of stroke in people with a medical condition called atrial fibrillation. This drug is less popular than comparable drugs. There are currently no generic alternatives to Pradaxa.
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    Precautions. If you have had heart valve surgery, talk to your doctor about the best medication for you. Do not stop taking any medication, including dabigatran, without talking to your doctor first. It is important that all your doctors and dentists know that you take dabigatran. Before having surgery or any medical/dental procedures, tell your doctor or dentist that you are taking this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may tell you to stop this medication before surgery. Follow your doctor’s directions carefully. Avoid getting injections into the muscles. If you must have an injection into the muscle (for example, a flu shot), ask for it to be given in the arm. This way, it will be easier to check for bleeding and/or apply pressure bandages. This medication may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink. This medication can cause heavy bleeding. To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. If you fall or injure yourself, especially if you hit your head, call your doctor right away.

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