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In terms of dosing, 50mg of naltrexone have the ability to block the effects of opioids for about 24 hours. Clinical studies suggest that doubling the dose will block opioid effects for 48 hours, while 150mg of naltrexone can provide blockage for approximately 72 hours.
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A dose of 50 mg once daily is recommended for most patients. The placebo-controlled studies that demonstrated the efficacy of Naltrexone hydrochloride tablets as an adjunctive treatment of alcoholism used a dose regimen of Naltrexone hydrochloride tablets 50 mg once daily for up to 12 weeks.
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No, you cannot get high on naltrexone. In fact, naltrexone is prescribed to treat opiate/opioid addiction and alcoholism by blocking the pleasurable and euphoric effects of these substances. It works by binding to opioid receptors in the central nervous system that these drugs normally occupy.
Differences between Naloxone, Naltrexone and Vivitrol: Naloxone (Narcan) is a short acting drug which will bring a patient out of an opiate overdose by stripping the opiate from the opiate receptor and is a life saving drug. Naltrexone, a short acting opiate/alcohol blocking agent has been used for the last 30 years. -
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