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Bactrim is an antibacterial synthetic product. Bactrim is prescribed for treatment of pneumonia and other diseases of respiratory, gastrointestinal systems, urogenital systems caused by bacterial infections which develop after surgery and others. It comprises two medicines sulfamethoxazole and trimethoprim. Together these medicines are active against streptococci, staphylococci, pneumococci, bacillus dysentery, typhoid fever, E. coli, Proteus, and ineffective against Mycobacterium tuberculosis, spirochetes, Pseudomonas aeruginosa.
Patients with chlamydia infections are treated with azithromycin, doxycycline, erythromycin, or ampicillin. Patients with chlamydia is often treated for gonorrhea with ceftriaxone or cefexime because of the high incidence of co-infection. Bactrim also does not treat gonorrhea.
BACTRIM (sulfamethoxazole and trimethoprim) is a synthetic antibacterial combination product available in DS (double strength) tablets, each containing 800 mg sulfamethoxazole and 160 mg trimethoprim; in tablets, each containing 400 mg sulfamethoxazole and 80 mg trimethoprim for oral administration.
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The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, respectively. However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section).
Tell your doctor about all medicines you may use before starting your treatment with Bactrim. It can change effects of the following medicines: anti-diabetic medications, diuretics, cyclosporine, digoxin, vaccines, tricyclic antidepressants. It can be co-administered with dofetilide or methenamine.