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Lanoxin is used to treat chronic heart failure, atrial fibrillation, to slow the heart rate in patients with chronic atrial fibrillation, a heart rhythm disorder of the atria.
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Digoxin, if it is effective, has some unique advantages compared with the existing heart failure medications. Provided toxicity is avoided, digoxin is remarkably free of side effects. Unlike other interventions for heart failure, except cardiac resynchronisation therapy,8 digoxin increases systolic blood pressure. It is extracted from the leaves of a plant called digitalis lanata. Digoxin increases the force of contraction of the muscle of the heart by inhibiting the activity of an enzyme (ATPase) that controls movement of calcium, sodium, and potassium into heart muscle. Calcium controls the force of contraction.
You should not use Lanoxin if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart). To make sure Lanoxin is safe for you, tell your doctor if you have: a serious heart condition such as „sick sinus syndrome“ or „AV block“ (unless you have a pacemaker); a recent history of heart attack; Wolff-Parkinson-White Syndrome (sudden fast heartbeats); kidney disease; a thyroid disorder; an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood);

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